Read e-book online Introduction to Computational Proteomics: Protein PDF

Introduction to Computational Proteomics introduces the sphere of computational biology via a targeted method that tackles the various steps and difficulties concerned with protein research, category, and meta-organization. The booklet begins with the research of person entities and works its method throughout the research of extra advanced entities, from protein households to interactions, mobile pathways, and gene networks.

The first a part of the booklet offers equipment for picking out the development blocks of the protein house, reminiscent of motifs and domain names. It additionally describes algorithms for assessing similarity among proteins in keeping with series and constitution research in addition to mathematical versions, resembling hidden Markov types and help vector machines, which are used to symbolize protein households and classify new situations.

The moment half covers equipment that examine better order constitution within the protein area in the course of the program of unsupervised studying algorithms, resembling clustering and embedding. The publication additionally explores the wider context of proteins. It discusses equipment for reading gene expression facts, predicting protein-protein interactions, elucidating mobile pathways, and reconstructing gene networks.

This ebook presents a coherent and thorough advent to proteome research. It deals rigorous, formal descriptions, in addition to certain algorithmic options and versions. every one bankruptcy contains challenge units from classes taught by way of the writer at Cornell college and the Technion. software program downloads, facts units, and different fabric can be found at biozon.org