New PDF release: Drug Discovery: Practices, Processes, and Perspectives

Sets forth the historical past, country of the technology, and destiny instructions of drug discovery

Edited by means of Jie Jack Li and Nobel laureate E. J. Corey, major pioneers in drug discovery and medicinal chemistry, this booklet synthesizes nice moments in historical past, the present kingdom of the technological know-how, and destiny instructions of drug discovery into one expertly written and arranged paintings. Exploring all significant healing parts, the booklet introduces readers to all features and stages of drug discovery, together with goal choice, organic trying out, drug metabolism, and computer-assisted drug design.

Drug Discovery beneficial properties chapters written by way of a world workforce of pharmaceutical and medicinal chemists. Contributions are in response to a radical evaluate of the present literature in addition to the authors' firsthand laboratory event in drug discovery. The ebook starts off with the historical past of drug discovery, describing groundbreaking moments within the box. subsequent, it covers such themes as:

• Target id and validation
• Drug metabolism and pharmacokinetics
• Central fearful approach drugs
• In vitro and in vivo assays
• Cardiovascular drugs
• Cancer drugs

Each bankruptcy incorporates a case learn, assisting readers know how technology is placed into perform all through all stages of drug discovery. References on the finish of every bankruptcy function a gateway to groundbreaking unique examine reports and reports within the field.

Drug Discovery is perfect for novices to medicinal chemistry and drug discovery, offering a accomplished evaluate of the sphere. Veterans within the box also will enjoy the views of prime foreign specialists in all points of drug discovery.